Language
English
Authors
Erdem Aktas • Ertugrul Sener • Pınar Uyar Gocun
Summary
We investigated the anti-inflammatory and
immunomodulatory effect of simvastatin on articular cartilage
via the inhibition of matrix metalloproteinase-3
(MMP-3), a matrix-degrading enzyme, in a mechanically
induced experimental osteoarthritis (OA) animal model.
Materials and methods Twenty-seven albino Wistar rats
Keywords
Simvastatin, Anterior cruciate ligament, Knee Osteoarthritis, Knee Osteoarthritis Treatment, Matrix
Metalloproteinase-3
